Package: idiffomix 1.0.0

idiffomix: Integrated Differential Analysis of Multi-Omics Data using a Joint Mixture Model

A joint mixture model is proposed that integrates information from gene expression data and methylation data at the modelling stage to capture their inherent dependency structure, enabling simultaneous identification of DMCs and DEGs. The model leverages a joint likelihood function that accounts for the nested structure in the data, with parameter estimation performed using an expectation-maximisation algorithm.

Authors:Koyel Majumdar [cre, aut], Isobel Claire Gorley [aut], Thomas Brendan Murphy [aut], Florence Jaffrezic [aut], Andrea Rau [aut]

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NEWS

# Install 'idiffomix' in R:
install.packages('idiffomix', repos = c('https://koyelucd.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/koyelucd/idiffomix/issues

Datasets:

On CRAN:

3.30 score 247 downloads 2 exports 50 dependencies

Last updated 2 months agofrom:2beadb29e1. Checks:1 OK, 7 WARNING. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKFeb 13 2025
R-4.5-winWARNINGFeb 13 2025
R-4.5-macWARNINGFeb 13 2025
R-4.5-linuxWARNINGFeb 13 2025
R-4.4-winWARNINGFeb 13 2025
R-4.4-macWARNINGFeb 13 2025
R-4.3-winWARNINGFeb 13 2025
R-4.3-macWARNINGFeb 13 2025

Exports:data_transformationidiffomix

Dependencies:clicodetoolscolorspacecowplotcpp11doParalleldplyredgeRfansifarverforeachgenericsggplot2gluegridExtragtableisobanditeratorslabelinglatticelifecyclelimmalocfitmagrittrMASSMatrixmclustmgcvmunsellnlmepillarpkgconfigplyrpurrrR6RColorBrewerRcppreshape2rlangscalesstatmodstringistringrtibbletidyrtidyselectutf8vctrsviridisLitewithr

idiffomix: integrated differential analysis of multi-omics data using a joint mixture model

Rendered fromvignettes.Rmdusingknitr::rmarkdownon Feb 13 2025.

Last update: 2024-12-18
Started: 2024-12-18