Package: idiffomix
Type: Package
Title: Integrated Differential Analysis of Multi-Omics Data using a
        Joint Mixture Model
Version: 1.0.0
Authors@R: c(person("Koyel","Majumdar",email="koyelmajumdar.phdresearch@gmail.com",
        role=c("cre","aut"),comment = c(ORCID = "0000-0001-6469-488X")),
        person("Isobel Claire","Gorley",email="claire.gormley@ucd.ie",
        role="aut", comment=c(ORCID="0000-0001-7713-681X")),
        person("Thomas Brendan","Murphy",email="brendan.murphy@ucd.ie", 
        role="aut",comment=c(ORCID="0000-0002-5668-7046")),
        person("Florence","Jaffrezic",email="florence.jaffrezic@inrae.fr",
        role="aut"),
        person("Andrea","Rau",email="andrea.rau@inrae.fr",role="aut",
        comment = c(ORCID = "0000-0001-6469-488X")))
Maintainer: Koyel Majumdar <koyelmajumdar.phdresearch@gmail.com>
Description: A joint mixture model is proposed that integrates
        information from gene expression data and methylation data at
        the modelling stage to capture their inherent dependency
        structure, enabling simultaneous identification of DMCs and
        DEGs. The model leverages a joint likelihood function that
        accounts for the nested structure in the data, with parameter
        estimation performed using an expectation-maximisation
        algorithm.
License: GPL-3
Depends: R (>= 3.5.0)
Imports: foreach, doParallel, parallel, mclust, stats, utils, edgeR,
        magrittr, ggplot2, scales, tidyr, dplyr, reshape2, gridExtra,
        grid, tidyselect, cowplot
Encoding: UTF-8
NeedsCompilation: yes
LazyData: true
LazyDataCompression: xz
RoxygenNote: 7.3.2
Suggests: rmarkdown, knitr
VignetteBuilder: knitr
Config/pak/sysreqs: libicu-dev
Repository: https://koyelucd.r-universe.dev
Date/Publication: 2024-12-18 17:23:51 UTC
RemoteUrl: https://github.com/koyelucd/idiffomix
RemoteRef: HEAD
RemoteSha: 2beadb29e1dd0c65b7f7c9384e8b03b723e5a95b
Packaged: 2026-10-04 14:39:24 UTC; root
Author: Koyel Majumdar [cre, aut] (ORCID:
    <https://orcid.org/0000-0001-6469-488X>),
  Isobel Claire Gorley [aut] (ORCID:
    <https://orcid.org/0000-0001-7713-681X>),
  Thomas Brendan Murphy [aut] (ORCID:
    <https://orcid.org/0000-0002-5668-7046>),
  Florence Jaffrezic [aut],
  Andrea Rau [aut] (ORCID: <https://orcid.org/0000-0001-6469-488X>)